Effectiveness of Recanalization of Chronic Total Occlusions: A Systematic Review and Meta-Analysis

at the time of review of outcomes of patients selected for CTO PCI based on procedural success with arterial patency compared with those with unsuccessful percutaneous revascularization and persistent vessel closure. Successful CTO PCI in these patient cohorts is associated with reduced mortality, angina, and need for coronary artery bypass surgery. The limitations of these investigations reviewed include possible selection bias of patients for percutaneous revascularization attempt and possible imbalance of unmeasured covariates and differences between groups. Overall, these data demonstrate a robust and consistent finding that successful revascularization or CTO patients results in improved outcomes compared with failed attempts.





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